The Massachusetts Institute of Technology has an urban campus that extends more than a mile (1.6 km). MIT campus encompasses a number of major off-campus facilities such as the MIT Lincoln Laboratory, the Bates Center, and the Haystack Observatory, as well as affiliated laboratories such as the Broad and Whitehead Institutes.

Harvard’s main campus is centered on Harvard Yard in Cambridge and extends into the surrounding Harvard Square neighborhood. The Yard contains administrative offices such as University Hall and Massachusetts Hall; libraries such as Widener, Pusey, Houghton, and Lamont; and Memorial Church.

Tory Row is the nickname historically given by some to the part of Brattle Street in Cambridge, Massachusetts where many Loyalists had mansions at the time of the American Revolutionary War, and given by others to seven Colonial mansions along Brattle Street. Samuel Atkins Eliot, writing in 1913 of the seven Colonial mansions making up Tory Row, called the area "not only one of the most beautiful but also one of the most historic streets in America”.

The Lexington Battle Green, also known as Lexington Common, is the historic town common of Lexington, Massachusetts, United States. It was at this site that the opening shots of the Battles of Lexington and Concord were fired on April 19, 1775, starting the American Revolutionary War. Now a public park, the common is a National Historic Landmark.

The Hancock–Clarke House is a historic house in Lexington, Massachusetts, that is a National Historic Landmark. The only extant residence associated with John Hancock was his boyhood home.

The site of the capture of Paul Revere is inside Minute Man National Historic Park, near the corner of Massachusetts Avenue and Mill Street. A circular memorial marks the site, with three commemorative markers - one of unknown origin, with two National Park Service markers flanking it.

Minute Man National Historical Park commemorates the opening battle in the American Revolutionary War. It also includes the Wayside, home in turn to three noted American authors.

There were at least eight iterations of the North Bridge constructed over four centuries. The current wooden pedestrian bridge, an approximate replica of the bridge that stood at the time of the battle, was built in 1956 and extensively restored in 2005.