The town of Lanciano is above all a cradle of art for the presence of numerous monuments, starting from the sanctuary of the Eucharistic Miracle which preserves the testimony of the oldest Eucharistic miracle of the Catholic world. Around the year 700, in the ancient church of San Legonziano, a Basilian monk expressed doubts about the presence of Christ in the Eucharist. During mass, the consecrated host and wine really turned into flesh and blood. The relics are kept in a monstrance that is admired by thousands of faithful.

Inside the Shrine of Manoppello is enclosed, in a case, what is recognized as the true Face of Jesus Christ. A legend tells that in 1506 a pilgrim presented himself to the physicist Giacomo Antonio Leonelli and gave him the precious gift. The veil remained in the Leonelli house until 1608, then was stolen by a soldier of fortune and sold to Donatantonio De Fabritiis and from these donated to the Capuchin Father Clemente from Castelvecchio From 1646 the Holy Face is exposed to the veneration of the people. It is a soft veil, the warp and the weft are intertwined in the form of a normal weaving. The cloth measures 17 x 24 cm and shows the image of a male face with long hair and a beard divided into bands; it is the only case in the world where the image is identically visible on both sides. No residues or pigments of color can be found. At the end of the seventies the Trappist nun Blandina Paschalis Schloemer, an expert iconographer, discovered that the Face of the Shroud of Turin and that of Manoppello