Sulla facciata della chiesa del Gesù Nuovo, è affissa la targa UNESCO con incisa la motivazione per la quale il centro storico di Napoli è divenuto patrimonio dell'umanità. La piazza, fulcro di alcuni dei più importanti monumenti di Napoli, ruota attorno al monumentale obelisco dell'Immacolata, maestosa guglia di marmo bianco e bardiglio posta al centro dello spiazzale.

The church of Gesù Nuovo, or of the Trinity Major, is a basilica church in Naples, located in piazza del Gesù Nuovo in front of the obelisk of the Immaculate Conception and the basilica of Santa Chiara. It is one of the most important and largest churches in the city, among the highest concentrations of Baroque painting and sculpture, on which some of the most influential artists of the Neapolitan school worked. Inside is the body of St. Giuseppe Moscati, canonized by Pope John Paul II in 1987.

The basilica of Santa Chiara, or the monastery of Santa Chiara, is a monumental building of worship in Naples, one of the most important and largest monastic complexes in the city.

Piazza San Domenico is one of the most important squares in Naples. It is located along the lower decumanus of the city, a short distance from Piazza del Gesù Nuovo. Being in the heart of the historic center of Naples, the square is the crossroads of two important streets of the city: Spaccanapoli (the lower east-west decuman) and via Mezzocannone (hinge that cuts south-north).

Via San Gregorio Armeno is a street in the historic center of Naples, famous for tourism for the artisan shops of nativity scenes. Today via San Gregorio Armeno is known all over the world as the exhibition center of the craft shops located here that now all year round make figurines for nativity scenes, both canonical and original (usually every year the most eccentric artisans make figurines with the features of characters of stringent topicality that perhaps stood out positively or negatively during the year).

The cathedral rises along the east side of the homonymous street, in a small square surrounded by arcades, and incorporates two other religious buildings that arose autonomously from the cathedral: the basilica of Santa Restituta, which houses the oldest baptistery of West, that of San Giovanni in Fonte, and the royal chapel of the Treasury of San Gennaro, which preserves the relics of the patron saint of the city. It is one of the most important and largest churches in the city, both from an artistic point of view, it is in fact the superimposition of several styles ranging from pure Gothic of the fourteenth century to the nineteenth-century neo-Gothic, which from a cultural point of view, hosting in fact three times a year the rite of the dissolution of the blood of San Gennaro.