Khor Virap is the most famous pilgrimage site in Armenia, as it is directly connected with the adoption of Christianity. As a state religion, Christianity in Armenia was adopted in 301 due to endeavors of Saint Gregory The Illuminator, who, before converting King Trdat The 3rd to Christianity, was imprisoned in the dungeon, over which a church of Khor Virap monastery was built in the 17th century. From the monastery one can admire the stunning view of the Biblical Mount Ararat.

Passing a narrow road, surrounded by rocks of hundred caves, one discovers a scene of harmony of architecture with nature. The monastery, enshrined with fine architectural solutions and luxurious embellishments, is one of the brightest examples of Armenian architecture of the 13th century. Noravank consists of St. Karapet, St. Gregory The Illuminator churches and St. Astvatsatsin (Holy Mother of God) two-storey church, which is notable for its ideal constructive and sculptural work.

Vayots Dzor and Areni village in particular has been the cradle of Armenian winemaking for millennia. "Hin Areni" wine factory opens up the doors of this region to the world to showcase the historic and indigenous Armenian grape varietals. At the winery the historic traditions of winemaking are well combined with state-of-the-art modern equipment. "Hin Areni" wine factory has the capacity to process over 250 tonnes of grapes.

Jermuk mineral waters gallery and waterfall. The famous health resort Jermuk is in the north-eastern part of Vayots Dzor. The mineral waters of Jermuk have been famous for their medicinal properties since early medieval. A special drinking gallery, along which pump rooms with mineral water are lined up, has been constructed for visitors. The water temperature varies from 30 to 50 degrees C.